Friday, September 14, 2018
Friday, December 6, 2013
Yes we can, mushrooms can change the weather
How Mushrooms Can Save the World
How Mushrooms Can Save the World
Crusading mycologist Paul Stamets says fungi can clean up everything from oil spills to nuclear meltdowns.
http://discovermagazine.com/2013/julyaug/13-mushrooms-clean-up-oil-spills-nuclear-meltdowns-and-human-health#.UqGzpidTDoa
Pioppino mushrooms (Agrocybe aegerita) induced tumor regression, reversing cancer in lab mice. The species also controlled blood sugar in diabetic mice.
HOW MUSHROOMS CAN SAVE THE WORLD
Wednesday, February 8, 2012
HOPKINS SCIENTISTS SHOW HALLUCINOGEN IN MUSHROOMS CREATES UNIVERSAL “MYSTICAL” EXPERIENCE
HOPKINS SCIENTISTS SHOW HALLUCINOGEN IN MUSHROOMS CREATES UNIVERSAL “MYSTICAL” EXPERIENCE
Johns Hopkins MedicineMedia Relations and Public Affairs
Media Contact: Eric Vohr
410-955-8665; evohr1@jhmi.edu
July 11, 2006
Rigorous study hailed as landmark
Using unusually rigorous scientific conditions and measures, Johns Hopkins researchers have shown that the active agent in “sacred mushrooms” can induce mystical/spiritual experiences descriptively identical to spontaneous ones people have reported for centuries.
The resulting experiences apparently prompt positive changes in behavior and attitude that last several months, at least.
The agent, a plant alkaloid called psilocybin, mimics the effect of serotonin on brain receptors-as do some other hallucinogens-but precisely where in the brain and in what manner are unknown.
An account of the study, accompanied by an editorial and four experts’ commentaries, appears online today in the journal Psychopharmacology.
Cited as “landmark” in the commentary by former National Institute on Drug Abuse (NIDA) director, Charles Schuster, the research marks a new systematic approach to studying certain hallucinogenic compounds that, in the 1950s, showed signs of therapeutic potential or value in research into the nature of consciousness and sensory perception. “Human consciousness…is a function of the ebb and flow of neural impulses in various regions of the brain-the very substrate that drugs such as psilocybin act upon,” Schuster says. “Understanding what mediates these effects is clearly within the realm of neuroscience and deserves investigation.”
“A vast gap exists between what we know of these drugs-mostly from descriptive anthropology-and what we believe we can understand using modern clinical pharmacology techniques,” says study leader Roland Griffiths, Ph.D., a professor with Hopkins’ departments of Neuroscience and Psychiatry and Behavioral Biology. “That gap is large because, as a reaction to the excesses of the 1960s, human research with hallucinogens has been basically frozen in time these last forty years.”
All of the study’s authors caution about substantial risks of taking psilocybin under conditions not appropriately supervised. “Even in this study, where we greatly controlled conditions to minimize adverse effects, about a third of subjects reported significant fear, with some also reporting transient feelings of paranoia,” says Griffiths. “Under unmonitored conditions, it’s not hard to imagine those emotions escalating to panic and dangerous behavior.”
The researchers’ message isn’t just that psilocybin can produce mystical experiences. “I had a healthy skepticism going into this,” says Griffiths, “and that finding alone was a surprise.” But, as important, he says, “is that, under very defined conditions, with careful preparation, you can safely and fairly reliably occasion what’s called a primary mystical experience that may lead to positive changes in a person. It’s an early step in what we hope will be a large body of scientific work that will ultimately help people.”
The authors acknowledge the unusual nature of the work, treading, as it does, a fine line between neuroscience and areas most would consider outside science’s realm. “But establishing the basic science here is necessary,” says Griffiths, “to take advantage of the possible benefits psilocybin can bring to our understanding of how thought, emotion, and ultimately behavior are grounded in biology.”
Griffiths is quick to emphasize the scientific intent of the study. “We’re just measuring what can be observed,” he says; “We’re not entering into ‘Does God exist or not exist.’ This work can’t and won’t go there.”
In the study, more than 60 percent of subjects described the effects of psilocybin in ways that met criteria for a “full mystical experience” as measured by established psychological scales. One third said the experience was the single most spiritually significant of their lifetimes; and more than two-thirds rated it among their five most meaningful and spiritually significant. Griffiths says subjects liken it to the importance of the birth of their first child or the death of a parent.
Two months later, 79 percent of subjects reported moderately or greatly increased well-being or life satisfaction compared with those given a placebo at the same test session. A majority said their mood, attitudes and behaviors had changed for the better. Structured interviews with family members, friends and co-workers generally confirmed the subjects’ remarks. Results of a year-long followup are being readied for publication.
Psychological tests and subjects’ own reports showed no harm to study participants, though some admitted extreme anxiety or other unpleasant effects in the hours following the psilocybin capsule. The drug has not been observed to be addictive or physically toxic in animal studies or human populations. “In this regard,” says Griffiths, a psychopharmacologist, “it contrasts with MDMA (ecstasy), amphetamines or alcohol.”
The study isn’t the first with psilocybin, the researchers say, though some of the earlier ones, done elsewhere, had notably less rigorous design, were less thorough in measuring outcomes or lacked longer-term follow-up.
In the present work, 36 healthy, well-educated volunteers-most of them middle-aged-with no family history of psychosis or bipolar disorder were selected. All had active spiritual practices. “We thought a familiarity with spiritual practice would give them a framework for interpreting their experiences and that they’d be less likely to be confused or troubled by them,” Griffiths says. All gave informed consent to the study approved by Hopkins’ institutional review board.
Each of thirty of the subjects attended two separate 8-hour drug sessions, at two month intervals. On one they received psilocybin, on another, methylphenidate (Ritalin), the active placebo.
In designing the study, researchers had to overcome or at least, greatly minimize two hurdles: the risk of adverse side-effects and the likelihood that the expectations of getting the test drug or the placebo would influence subjects’ perceptions.
To lessen the former, each subject met several times, before drug sessions began, with a reassuring “monitor,” a medical professional experienced in observing drug study participants. Monitors stayed with them during the capsule-taking sessions. Actual trials took place in a room outfitted like a comfortable, slightly upscale living room, with soft music and indirect, non-laboratory lighting. Heart rate and blood pressure were measured throughout.
The researchers countered “expectancy” by having both monitors and subjects “blinded” to what substance would be given. For ethical reasons, subjects were told about hallucinogens’ possible effects, butalso learned they could, instead, get other substances-weak or strong-that might change perception or consciousness. Most important, a third “red herring” group of six subjects had two blinded placebo sessions, then were told they’d receive psilocybin at a third. This tactic-questionnaires later verified-kept participants and monitors in the dark at the first two sessions about each capsule’s contents.
Nine established questionnaires and a new, specially createdfollowup survey were used to rate experiences at appropriate times in the study. They included those that differentiate effects of psychoactive drugs, that detect altered states of consciousness, that rate mystical experiences and assess changes in outlook.
The study, Griffiths adds, has advanced understanding of hallucinogen abuse.
As for where the work could lead, the team is planning a trial of patients suffering from advanced cancer-related depression or anxiety, following up suggestive research several decades ago. They’re also designing studies to test a role for psilocybin in treating drug dependence.
The study was funded by grants from NIDA and the Council on Spiritual Practices.
Una McCann, M.D., William Richards, Ph.D., of the Johns Hopkins Medical Institutions and Robert Jesse of the Council on Spiritual Practices, San Francisco, were co-researchers.
The commentaries on this study that appear in this issue of Psychopharmacology are available at: http://www.hopkinsmedicine.org/Press_releases/2006/GriffithsCommentaries.pdf
and include remarks by:
*Hopkins neuroscientist and Professor of Neuroscience, Solomon Snyder, M.D.
*Former NIDA head Charles Schuster, Ph.D., now Distinguished Professor of Psychiatry and Behavioral Neuroscience at the Wayne State University School of Medicine
*Herbert Kleber, M.D., a professor of psychiatry at Columbia University and a former deputy director of the White House Office of National Drug Control Policy (ONDCP)
*David Nichols, Ph.D., with the Purdue University School of Pharmacy and Pharmaceutical Sciences
*Harriet de Wit, Ph.D., at the University of Chicago Department of Psychiatry. DeWit is the editor of Psychopharmacology.
Related links: Q&A is with Roland Griffiths, the study’s lead researcher:http://www.hopkinsmedicine.org/Press_releases/2006/GriffithspsilocybinQ
Psychopharmacology:
http://www.hopkinsmedicine.org/Press_releases/2006/GriffithsPsilocybin.pdf
http://www.hopkinsmedicine.org/press_releases/2006/07_11_06.html
Wednesday, June 9, 2010
Terence McKenna by Robert Venosa
Time for the monkeys to move into hyperspace!
Nature is ourselves, to be cherished and explored."
—Terence McKenna
One of the principle philosophical underpinnings for our assumption of 2012 being a planetary tipping point comes from our years of working with the late Terence McKenna. In 1996 we presented the Terence McKenna Prophets Conference Timewave Zero tour of America beginning at the Cathedral of Saint John the Divine in New York then moving across the country, ending at UCLA in Los Angeles . Combine fractal mathematics with the I-Ching into a computer program created with a giant punch card computer at Berkeley in the 1960s, and you come up with a graph of history measuring novelty (new things and events) vs. habit (nothing new). From this you come to a Zero Point on December 21, 2012, which as we know happens to also be the end of the Mayan long-count. Interesting.
www.youtube.com/watch?v=
So, back in the 90s we brought together for an exciting weekend workshop on Maui, Hawaii Terence McKenna and leading fiction author and close friend of our's and McKenna’s, Tom Robbins. Participants came from around the world for this one time mind boggling event, which we agreed not to record. But here is some of what Tom Robbins wrote about McKenna in the forward to McKenna’s book The Archaic Revival which is reminiscent of the Maui gathering
“Our problems today are more complex and more threatening than at any time in history. Sadly, we cannot even begin to solve those problems, because our reality orientations are lower than a snowman’s blood pressure. We squint at existence through thick veils of personal and societal ignorance, overlaid with still more opaque sheets of disinformation, thoughtfully provided by the state, the church, and big business (often one and the same). The difference between us and Helen Keller is that she knew she was deaf and blind.
“Radical problems call for radical solutions. Conventional politicians are too softheaded to create radical solutions and too fainthearted to implement them if they could, whereas political revolutionaries, no matter how well meaning, ultimately offer only bloodshed followed by another round of repression.
“To truly alter conditions, we must alter ourselves—philosophically, psychologically, and perhaps, biologically. The first step in those alterations will consist mainly of cutting away the veils in order that we see ourselves for that transgalactic Other that we really are and always have been. Terence the Tailor has got the sharpest shears in town. And he’s open Sundays and holidays. Once the veils are severed, we, each of us, can finally start to attend to our self-directed mutagensis.
“The flying saucer is warming up its linguistic engines. The mushroom is shoving its broadcasting transmitter through the forest door. Time for the monkeys to move into hyperspace! It’s going to be a weird, wild trip, but, guided by the archaic, Gaia-given gyroscope, we can commence the journey in a state of excitement and hope. With his uniquely secular brand of eschatological euphoria, Terence McKenna is inviting us to a Doomsday we can live with. Be there or be square.”
—Tom Robbins
From the Grasslands to the Starship by Terence McKenna
23-25 July 2010
Conference Information: www.greatmystery.org/events/
In-Depth Post-Conference Workshops 26-27 JULY 2010
Exhibitor Information: www.greatmystery.org/events/
Download an Event Flyer to share with friends Color or Black/White.
The purpose of this GROUNDBREAKING conference is to explore a radically different, more optimistic interpretation of the Mayan prophecy – as referring to the end of the world as we have known it. In addition to predicting a physical destruction of the material world, the Mayan prophecy might refer to death and rebirth and a mass inner transformation of humanity. The conference brings together JOSE ARGUELLES, FLORDEMAYO, ANDREW HARVEY, BARBARA MARX HUBBARD, JOHN MAJOR JENKINS, JOHN KIMMEY, JOHN PERKINS, DANIEL PINCHBECK, LLYN ROBERTS, RICHARD TARNAS, and MIGUEL ANGEL VERGARA and in the beautiful setting of Vancouver, Canada. Following the conference will be in-depth post-conference workshops. We hope you can join us for this powerful and inspiring event.
ADDITIONAL WRITINGS
Closing Of The Cycle : The Last Days and What Is To Be Done by Jose Arguelles
Guardians of the Light by John Perkins
The Revolution that the Divine Mother is Preparing by Andrew Harvey
Reflections on John Kimmey by Hannah Janulewicz
The Dalai Lama and The Economic Hitman by John Perkins
Our Crisis Is The Birth Of A Cocreative Universal Humanity by Barbara Marx Hubbard
Our Moment in History as an Initiation for Humanity by Richard Tarnas
The Hinge Of A Transition In Our Species’ Awareness by Daniel Pinchbeck
Gazing Into The Cosmic Center December 21, 2012 by John Major Jenkins
An Alliance of Prayer, Education and Healing for Our Mother Earth by Flordemayo
2012 Planetary Evolution by Barbara Marx Hubbard
A Radioactive Nuisance to All Those in Power by Andrew Harvey
1000 Days to Zero Point 2012 by Jose Arguelles
The Eternal Fire of Transformation by John Major Jenkins
Planetary Whole System Design Science by Jose Arguelles
Sacred Activism and the Birth of the Divine Humanity by Andrew Harvey
Something Monumental Is Going To Happen by Mayan elder Flordemayo
This Is It by John Eesawu Kimmey
2012 and Other Indigenous Prophecies for Transformation by Llyn Roberts
How Do We Get Ready for 2012? by Barbara Marx Hubbard
It Happened In Cancun a preview for Vancouver
2012 : The Primal World Ensouled - Richard Tarnas
The True Meaning of 2012 by John Perkins
CONFERENCE SPONSORS
New Awareness - The Review for Spiritual Seekers.
Banyen Books & Sound - A Watering Hole for the Spirit on the World Wide Web.
Conscious Living Radio - To expand your consciousness.
Reality Sandwich - Evolving consciousness, bite by bite.
Lilipoh ~ the spirit in life
Gaia Media - For a holistic and up to date understanding of our existence and the potential of human consciousness.
Shaman Portal - The global resource for all things shamanic.
http://www.greatmystery.org/
Wednesday, December 30, 2009
ITS A LIGHT MATTER by Fly Agaric 23
It's alight matter
By flyagaric23
On August 5th, 1945 a Mushroom cloud appeared over Hiroshima, illustrating humanities latest technological breakthrough in Killingry: the ability to kill more and more people in less and less time. 21st century technology can either help people to live joyously and cooperatively or force them to die quicker. The choice is ours. But the hours are not all ours. The first neurotransmitter known to science; Acetylcholine, was identified in 1914 at the breakout of the first world war by Henry Hallett Dale while doing research on heart tissue, Henry went on to win a nobel prize for his rediscovery. The devastating killingry made possible by biological nerve weapons of mass destruction, and other secret nerve agents, are partly due to their inhibition of acetylcholinesterase in the victims. Constant stimulation of the muscles glands and the central nervous system are the terrible symptoms. Popular insecticides inhibit this enzyme too and destroy targeted insects, such as fungas gnats and green fly.
On a more positive tip, Muscarine, a subdivision of Acetylcholine and a neurotransmitter in both the peripheral and central nervous system, can be used to treat Alzheimer's disease and other complications involving abnormal muscle relaxation. The stimulation of the muscle glands through Muscarine acts as an example of a drug being used intelligently and positively as a medicine to help prolong life and help the ill, rather than provoking illness and leading to the annihilation of life.
During the rainy season in the sonoran deserts in Colorado, America, people make a sacred pilgrimage to communicate with little green non-human entities. Small, soft and velvety to touch, with cute little emerald heads that are full of jewles, these holy amphibian drug dealers can each individually deliver enough psychopharmacological energy force to launch, as Ralph Metzner puts it: six to eight adult human beings, potentially, into cosmic hyperconsciousness; into the heart of creation, while returning them safely to their original human form shortly afterwards. A loving example of inter-species communication between mankind and amphibians.
Paradoxically entomology is the scientific study of insects, while etymology is the study of the origins of words. Drosophila_melanogaster is the common species of fruit fly used in genetics experiments ever since GM kicked off around 1910 AD. Most of our modern pharmacological technology and genetic advances are indebted to humble flies while various chemical discoveries are due to extracts from their toadstool namesake: fly agaric.
Italian Ethnobotonist and Ethnomycologist Giorgio Samorini came up with a brilliant new hypothesis called the Lazarus fly, published in his illuminating book; Animals and Psychedelics. This enchanting social-biological observation provides strong scientific evidence for a minded symbiotic relationship between toads, flies and fungi. Buzzillions of flies and fungus gnats throughout history have licked Amanita Muscaria and become as inebriated as Tim Finnegan, stoned, drunken, delirious meals for hungry toads, and other forest-floor foragers who may or may not have picked up this evolutionary advantage, probably tuned in while hanging around mushrooms. This strong, undiluted 70% proof of interspecies communication occuring in forests all over the natural world, illuminates an important etymological keystone; a symbiosis so ancient that it's imediate implications demand an entire scientific and poetic revolution. The buzz term in this field is zoopharmacognosy: the study, celebration and liberation of animals, bugs and plants that mindfully use themselves as inebriating medicine as a kind of novel evolutionary advantage.
Mycoremediation is a term spun by mycologist Paul Stamets and roughly translates as environmental renewal by using fungus. The relative scientific facts about mycoremediation are inspirational for all critterkind facing global meltdown and mindless industrial, global pollution. Fungi have their own kingdom of nature, yet every individual spore is a Tsar: they do not have leaders or Kings in their fungal kingdom, in contrast to human oligarchy. They charitably recycle billions of tons of natural and man made waste products for free so that plants, animals and humans benefit with furtile soils and healthy nutrients to live together happily with. In kaleidoscopic contrast we have the civilized Homo sapien species, who are without shadows of doubt, the greatest natural disaster to explode themselves on this beautiful and life sustaining free planet. Fungus; through their bioremediation are our saviors in some sense. Our shit munching little helpers in another. Literally: mothers little helpers.
Muscarine occurs inside the fetching fly agaric species of mushroom alongside some other psychopharmacological secret agents: ibotenic acid, muscazone and muscimol. Fly agaric and many other fungi in the agaric family are spread far and wide across planet earth. Due to the lack of fungal fossil records we have no specific scientific data pinpointing exactly how long these toadstools have been here, although it's safe to say longer than homo sapiens. Scientific research upon this particular species of fungus has led to many compounds used to increase longevity. Alternatively, other fly agaric extracts can dramatically paralyze biological life, much like usury paralyzes wealth by asphyxiating the natural abundance of nature, blocking her will. Some scholars such as the part time banker at J.P Morgan, and part time mycologist; Richard Gordon Wasson, have suggested that fly agarik is the mythical plant/drug/drink known widely as Soma; highly regarded in the sacred Hindu texts called the Rig Vedas.
Terence Mckenna has proposed that psylocybin containing mushrooms and not Amanita mushrooms maybe a more fitting candidate for the mighty Soma complex due to their stronger psychoactive properties. Other theories propose Soma to be an alchemical combination of various psychoactive vegetables. Thousands of years ago Soma was celebrated as the divine ambrosia of immortality. Today scientists can show how the chemical muscarine lives up to this description by providing useful medical drugs that help prolong life. The great Aldous Huxley deployed SOMA as a literary device in his novel Brave New World, Soma's function in this novel was an opiate of the masses substituting religion and other stimulants popular with Homo sapiens. This excellent distopian device scares me relatively more than Eric Blair's Big Brother and his similar critically paranoid, Nineteen Eighty Four. Although to me, both of these novels seem like fairy stories when compared with the terrifying phenomenon known worldwide as satan claus.
Spearheading the rapidly expanding field of evolutionary epistemologyThe Lazarus fly provides a stunning example of a tight biosemiotic epistemological fit; snug as a bug in a rug. An ancient motherfucking most mysterious matrix tale. An epic love story providing semiotic insights into one of the strangest sociobimaybelogical, tragic/comic romances upon spaceship earth. That's until some entity proposes superior scientific research data to challenge it.
The term to identify flies in latin is musca. Semiotics used as a method applied to fairy myth helps to refine a linguistic approach and attempts to find the 'words' of it's universal lunguage. Many people who choose to ingest psychedelicsgenerally experience a dramatically increased sense and sensibility of light, ranging from tranquil and soft star sparkles, flares, dancing multicolored flames; and the warm sense that billions of torches are searching through fiber-optic energy channels in their body. ToThunder. Lightening. Flashes of explosive photonic bombardment. From all quarters. Blinding. Fractal. Hyperspatial travel. Annihilation. Super nova neural explosions. Atomic detonation of physical boundaries. Energy flashes. Repeating visions. Safely tucked away behind the eyelids.
According to some Christian theology God muttered let there be light, and then, there was light. Bioluminescence is a relatively knu scientific term describing biological cells that emit light photons known as biophotons. Many of the brighter investigative researchers within this glowing field propose that DNA RNA is perpetually emitting these biophotons, and has been doing so since the first RNA DNA molecular poets resurrected themselves upon spaceship Earth. Because of the relatively weak broadcasting strength of these biophotons only recently has modern science and it's post-modern instrumentation rediscovered these ancient auras and properly acknowledged their universality among all RNA DNA coded critters. In the Tibetan book of the Dead there are six lights which correspond to six realms of existence - traditionally, the realm of the gods, jealous gods (asuras), humans, animals, hungry ghosts and hell beings. These lights are also known as the lower lights.
An ever growing population of anthropologists and scientists have visited and participated in ancient sacred vegetable rites and ceremonies and journeyed back to a western scientific paradigm with reality shattering alternative maps, models and novel metaphors. Brave Knu tempronauts vividly describe incredible visions; tales of serpents, jaguars, Pink river dolphins, insectoid timespace traveling anthropologists, many headed monsters with gnashing teeth, light beings, diamond encrusted dancing angels, self transforming basketball elf chemists, E.T's, ghosts of vegetation spirits, deities, superluminous skyladders leading to star systems. This dissolution of boundaries between human, animal, insect, vegetable and amphibian kingdoms into a twilight of pastiche, seems, most likely to me, that under the extra sensory perceptive conditions of certain psychopharmacological agents, the RNA DNA emitted biophotons that are contained within all life on earth suddenly appear detectable to our interacting human nervous system. We literally begin to see the photons, reflect, and then feel what's the matter. And we interpret this light according to our own individual glosses, our neuropsychological and neurosemantic belief systems. I'm doing this right now, and so are you!
The perceived fire inside of fireflies or the lightening inside of lightening bugs is known to scientists as Luciferin. Jellyfish, and Antarctic Krill also contain Luciferin. These creatures translate and amplify the light to such a degree that they appear to human and other sufficiently accomplished seeing critters, as ill with a case of the luminous. Yet, if we could increase our sensitivity to light then maybe all DNA RNA based life would appear illuminated?
Coincidently, illumination or enlightenment [the concept] often appears to critters under the influence of psychoactive compounds or what may be more poetically called entheogens [messengers of metempsychosis from within]. And God said: let there be light, but the meter remained and empty woid. flyagaric23
Track:
Quantum mechanix